Slugger Alex Rodriguez has sued Major League Baseball and the players union, seeking to overturn evidence that he used banned substances, The Associated Press and ESPN reported.

An arbitrator Saturday upheld most of Rodriguez's 211-game doping suspension, keeping him out of the 162-game 2014 regular season and the postseason.

The ruling by Major League Baseball arbitrator Fredric Horowitz will not only cost Rodriguez $25 million in salary, it also further clouds the groundbreaking career of a player who will turn 40 during the 2015 season.

The 162-game suspension -- which is the most severe punishment in baseball history for doping -- highlights baseball Commissioner Bud Selig's recent high-profile crackdown on performance-enhancing drugs.

In the lawsuit, Rodriguez claimed that the players union "completely abdicated its responsibility to Mr. Rodriguez to protect his rights," the AP reported. This created a climate "in which MLB felt free to trample" on his rights, the wire service said.